Semaglutide titrates from 0.25 mg to 2.4 mg
Landmark trials such as SUSTAIN and STEP demonstrated significant reductions in HbA1c levels and body weight in T2DM and obesity ( Although direct head-to-head evidence robustly favors tirzepatide for weight loss and glycemic control, comparative cardiovascular outcomes currently rely on contextual data from independent cardiovascular outcome trials and real-world observational studies
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GLP-1 Medications: What They Are and How They Work GLP-1 medications represent a class of prescription drugs that were initially developed for blood sugar management in type 2 diabetes but have demonstrated significant effects on weight loss
Licensed options include semaglutide (Wegovy), tirzepatide (Mounjaro), liraglutide (Saxenda), and orlistat, all available through NHS or regulated private services
