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Compared to the original peptide, which is rapidly degraded by enzyme dipeptidyl peptidase-4 (DPP-4) in 1.5 min [21], GLP-1 RAs show a long-term action in resisting the degradation through DPP-4

Carotenoids and flavonoids can reduce the damage caused by UV rays, remove tanning and prevent sun spots

They can also affect dopamine release

If diarrhea continues beyond 8 weeks or worsens significantly, discussing your symptoms with your healthcare provider helps rule out other causes and guides treatment adjustments

For a deeper dive, this semaglutide side effects guide explains why it can show up early in treatment and how people often manage it