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NICE guideline NG69 recommends cognitive behavioural therapy for eating disorders (CBT-ED) as the first-line treatment, typically delivered over 16-20 sessions

In one phase 2 study: Pancreatitis was reported in about 0.4% of participants (1 out of 267) Gallbladder issues affected roughly 1.1%, with no cases in the placebo group Heart rhythm changes were reported more often in people taking retatrutide (about 6% compared to 3% with placebo) Liver enzyme increases were rare (around 1%), and overall liver health markers stayed stable over time

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2023;39(6):e2-3

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