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Finally, the beneficial effects of this antibody on weight and metabolic parameters were significantly potentiated by concomitant therapy with the GLP-1 analogues dulaglutide and liraglutide (149)

Weight loss from semaglutide is due to an overall decrease in ones intake of calories from food and drink

Because of the Trp33 dependence, any binding, functional, or in-vivo study must use a human or humanized (Trp33-containing) GLP-1 receptor

This suggests that although both medications cause similar types of side effects, the severity or persistence may be greater with liraglutide for some people