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Start titration exactly as recommended, because how quickly you escalate matters as much as what you change on the plate: Begin 0.25 mg once weekly for weeks 14 Move to 0.5 mg weekly for weeks 58 Continue gradual increases to your maintenance dose Pair careful titration with targeted, testable adjustments to meals, movement, and simple OTC supports to reduce the risk of severe gas and other GI symptoms as you adapt

Canadas patent has already lapsed, enabling potential launches as early as January 2026 Active litigation in India and China is unlikely to delay generic entry beyond March 20th 2026

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Holman RR, Bethel MA, Mentz RJ, et al