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In a 48-week phase 2 trial in people with T2D and obesity, 10 mg/kg bimagrumab was associated with a marked reduction of fat mass (20.5% vs

Therefore, even though peroxisomal -oxidation may have been up-regulated in the d-carnitine group, this would have been insufficient to compensate for the depressed mitochondrial -oxidation of FA

Despite this, the peptide is widely available online in injectable and ingestible forms, often sold with labels that say for research use only, in an effort to hide from regulatory action

In addition to Munger, key support for this study was provided by Wilmot investigators Brad Mills, PhD, and Brian Altman, PhD.

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