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Case reports in the medical literature have documented Wernicke encephalopathy and beriberi in GLP-1 users with severe B vitamin deficiencies

Alaa H, Abdelaziz M, Mustafa M et al (2023) Therapeutic effect of melatonin-loaded chitosan/lecithin nanoparticles on hyperglycemia and pancreatic beta cells regeneration in streptozotocin-induced diabetic rats

They Survive on Just a Few Meals a Year Gila monsters have a unique metabolic adaptation: they can gorge on one meal, storing body weight as fat in their thick tails, and then go months without eating again

Each of these therapies represents a major advancement in the science of metabolism and body composition