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Inhibition of hypoxia-induced autophagy was shown to disrupt pSTAT3 signaling through accumulation of p62, which selectively induces pSTAT3 degradation by the proteasome system and thereby restores cytotoxic T-cell mediated killing of tumor cells (273)

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GSH therefore enables the recycling of vitamins C and E, again protecting the body from oxidative stress (1)