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Also, intracellular, oxidants are produced as an effect of the combined environmental exposure described the exposome, which involves molecular factors such as toxicants, nutrients, drugs, and pollutants as well as physical stressors (UV, X-ray, and other ionizing radiation) and psychological stressors (lifestyle)

Primary glutamatergic deficit, likely originating from aberrant neuron-glia interactions, leads to an early GSH excess via diversion of GSH-glutamate metabolic pathways

Tumor-associated macrophages: An effective player of the tumor microenvironment

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Kensler TW, Roebuck BD, Wogan GN, Groopman JD (2011) Aflatoxin: a 50-year odyssey of mechanistic and translational toxicology