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Epigenetic changes of DNA repair genes in cancer

Signaling events leading to EMT activate mesenchymal state in the cancer cells, which was associated with increased frequency of cancer stem cells (CSCs) sometimes also termed tumor-initiating cells [25]

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[DOI] [PubMed] [Google Scholar] 44.Salomon S., Guignant C., Morel P., Flahaut G., Brault C., Gourguechon C., Fardellone P., Marolleau J.P., Gubler B., Goeb V