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Mrquez, J., Mats, J

Paracetamol-Induced Glutathione Consumption: Is There a Link With Severe COVID-19 Illness

Conclusions In recent years, parallel to the increase in clinical and survival benefits that we have obtained with the widespread use of OL-HDF over conventional HD, we have also witnessed a change in the profile of dialysis patients who are increasingly older and with more comorbidities, and continue to have problems associated with inflammation, oxidative stress, and excess cardiovascular morbidity and mortality

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The bifunctional enzyme, formimidoyltransferase cyclodeaminase (also called glutamate formiminotransferase), then transfers the formimino group from N -formimidoyl-L-glutamate (commonly referred to as FIGLU) to THF yielding N 5 -formimino-THF (5-fominino-THF) and glutamate