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Calorie restriction with physical activity encompassing resistance exercise during weight loss has been shown to counteract high turnover bone loss compared with calorie restriction alone

There are some opportunities to improve on the current drugs, Campbell said

Appetite regulation involves both physiological hunger and cognitive drive, which is why this change can feel noticeable even before significant weight loss occurs

Optimal gut health also influences how the body stores and utilises fat, promoting its breakdown and preventing excessive accumulation. By maintaining a diet rich in fibre, fermented foods and prebiotics, individuals can support their gut health and improve their weight management efforts