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Zepbound is the first and only obesity treatment of its kind that activates both GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) hormone receptors

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People taking GLP-1 drugs like Ozempic and Wegovy to help treat obesity lose an average of 1520% of their body weight

OptumRx, 2026 formulary update and prior authorization criteria In February 2026, OptumRx removed the BMI requirement from its cardiovascular reauthorization criteria for Wegovy, simplifying continued authorization for UHC members using the CV indication

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