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RNR subunit expression is controlled by the cell cycle machinery to match the need for nucleotide synthesis to cell proliferation (Eriksson et al, 1984

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Glutathione, Aging, and Oxidative Stress Oxidative damage is a major focus in aging research, and glutathione is central to many of these investigations: Glutathione levels appear to decline with age in many tissues, including the brain, with a corresponding increase in oxidative markers after a delay