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A mice model for PCOS has been developed (ob/ob mice that are also leptin deficient), where mice are: - obese - hyperglycemic - hyperinsulinemic - insulin-resistant - exhibiting increased TNF-a and IL-6 levels, which promotes the state of chronic low-grade inflammation

La transicin del extracto de polipptido natural al tetrapptido sinttico Epithalon represent una dcada de trabajo identificando qu fragmento de la epitalamina portaba la actividad biolgica central

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10.3389/fneur.2020.594613 Front