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B-100 complex can interfere with other medications including but not limited to levodopa, medicines containing oestrogen, hydrazine, certain anti epileptic drugs, phenobaritone, phenytoin, immunosuppressants and some medicines used to treat infections such as isoniazid, pyrazinamide, cycloserne and penicillamine

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Its g-ng dose range applied alone, without carrier addition, application including also via per-oral route, clinical evidence, and toxicology without LD1, can ascertain practical applicability