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As the Lactobacillaceae and Prevotellaceae families were shown to decrease in CKD patients, the supplementation with probiotics including Lactobacillus acidophilus was performed in CKD patients [14]

In addition, metabolic abnormalities due to specific, inherited enzyme deficiencies can affect the liver

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A unifying feature is their ability to mitigate oxidative stressfor example, many flavonoids, alkaloids, and saponins activate the Nrf2/ARE pathway, upregulating endogenous antioxidant enzymes (such as superoxide dismutase and glutathione peroxidase) to neutralize excess reactive oxygen species (Wang Q

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