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These changes suggest that GCH1 overexpression does not protect all PUFA-PLs, but selectively blocks the oxidation of specific PUFA-PLs

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We can therefore consider glutathione to be a safe storage for cysteine

This demethylation leads to destabilization of the mRNA, resulting in reduced CHAC1 protein levels and inhibition of ferroptosis

The PTEN/PI3K/Akt signaling pathway mediates HMGB1-induced cell proliferation by regulating the NF-B/cyclin D1 pathway in mouse mesangial cells