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Valverde P, Healy E, Jackson I, et al

Belapectin, a galectin-3 inhibitor, was well tolerated in a year-long biweekly infusion but showed no significant effects on hepatic venous pressure gradient (HVPG) or fibrosis in a phase 2B study involving 162 patients with MASH, cirrhosis, and portal hypertension

As the pathological immune response in HDFN can arise early in gestation and persist throughout a pregnancy, dosing of FcRn antagonists to treat HDFN would have to be continuously performed throughout gestation

The nervous system controls many automatic processes in the body, including temperature regulation

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