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Functional annotation highlighted genes potentially involved in AFB1 detoxification, including predicted cytochrome P450, epoxide hydrolase ( LAP2 ), glutathione-S-transferase ( URE2 ), and the ABC transporter ( YCF1 ), suggesting pathways for AFB1 activation, glutathione conjugation, and vacuolar sequestration

Brainstem : The area postrema, nucleus tractus solitarius, and dorsal motor nucleus of the vagus contain both GLP-1-producing neurons and GLP-1 receptors

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For example, studies have discovered that microbial metabolites, such as hydrogen sulfide (H 2 S), short-chain fatty acids (SCFAs), and tryptophan, in particular, considerably regulate mitophagy in SLE (114116)