In 2016, concerns regarding retinopathy associated with GLP-1 were first raised in the Semaglutide Unabated Sustainability in Treatment of T2DM (SUSTAIN) 6 trial with semaglutide [89]
This is why many providers prefer 20mg/ml for patients they expect to titrate to higher doses
According to the FDA prescribing information for both Ozempic and Wegovy, nausea, vomiting, diarrhea, abdominal pain, and constipation occur in a significant proportion of patients, particularly during dose escalation
Emerging research including new guidance from the InfantRisk Center suggests that the biggest concern during breastfeeding may not be medication transfer into breast milk , but whether the parent is able to consume enough calories and nutrients to support milk production
This marked a key moment in the companys diabetes strategy, supported by strong clinical results showing better blood sugar control and weight loss