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Highest K a value of 1.5 h 1 was obtained in hydroxychalcone followed by diosgenin (1.1 h 1 ) and the least of case of charantin, 0.46 h 1

the direct clinical evidence here is for elamipretide (SS-31), not every peptide

[DOI] [PubMed] [Google Scholar] Levine GN, Frei B, Koulouris SN, Gerhard MD, Keaney JF, Jr, Vita JA

The analytical gradient was 340% solvent B over 42 min, rising to 95% solvent B by 45 min, followed by a 4 min wash at 95% solvent B and equilibration at 3% solvent B for 10 min