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2023 Aug 26;402(10403):72030
IGF binding proteins in cancer: mechanistic and clinical insights
(1) Regulatory and scalability gaps: standardized protocols for polymeric carrier scalability, sterilization, and long-term stability are lacking, with advanced systems (e.g., PEGylated uricase and biomimetic nanosystems) requiring rigorous immunogenicity (anti-drug antibodies) and cost-effectiveness evaluations
Therefore, it is important to be cautious about quick-fix solutions and consult a healthcare professional before opting for such products
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