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Long-term safety data from human use is limited

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Protumor neutrophils, on the other hand, are immunosuppressive and foster tumor invasion, metastasis, and angiogenesis by releasing NE and other proteins, e.g

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The efficacy and safety of melatonin in concurrent chemotherapy or radiotherapy for solid tumors: a meta-analysis of randomized controlled trials

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We therefore used a strategy based on MRP1/MRP2 chimeras to screen for regions and residues of MRP1 that are essential for the CS agents-mediated stimulation of GSH efflux and attempted to discriminate these regions from that involved in drug transport

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