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a clue to the mechanism of 5-oxoprolinuric acidosis

In these studies, children with mild-to-moderate asthma had significantly lower concentrations of exhaled GSH than healthy controls who were further associated with increased malondialdehyde formation, a marker of lipid peroxidation (57, 70)

15,16 One setting in which metformin is sometimes considered first-line treatment is in adolescents with PCOS, although oral contraceptives are important as well

Glutathione is often called the master antioxidant because, unlike other antioxidants such as vitamin C or vitamin E that are consumed in a single interaction with a free radical, glutathione can be regenerated and recycled by the enzyme glutathione reductase

Theyve also observed lower GSH levels in those with diabetes compared to normoglycemic individuals and were able to identify defects in antioxidant function in impaired glucose intolerance