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In summary: Zn is a key component of CA

To maintain a steady, endogenous supply of cysteine for glutathione production, the body relies heavily on the transsulfuration pathway

doi: 10.3389/fcimb.2024.1361660 Received 26 December 2023 Accepted 19 February 2024 Published 05 March 2024 Volume 14 - 2024 Edited by Xiangtian Yu, Shanghai Jiao Tong University, China Reviewed by Shigefumi Okamoto, Osaka University, Japan Xin Sun, The First Affiliated Hospital of Soochow University, China Updates Copyright 2024 Song, Bai, Liu, Zhai and Zhang

CS exposure depleted ELF GSH levels by 4 hours from 100 M to 25 M, which was roughly the level where it remained until the end of the CS exposure (Figure 3A)