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Available from Citation on PubMed Rubio-Gozalbo ME, Bakker JA, Waterham HR, Wanders RJ
2022;66:e2200173
Clinical studies have confirmed that PD patients show concurrent elevation of p -MLKL (a marker of necroptosis), IL-1 (a marker of pyroptosis), and 4-HNE (a marker of ferroptosis) in cerebrospinal fluid, which are positively correlated with the degree of SN neuronal loss, suggesting the synergistic activation of multiple death pathways during disease progression [163,164,236]
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SGLT-2 inhibitor and GLP-1 receptor agonist treatment for patients with nonalcoholic fatty liver disease and type 2 diabetes mellitus: is their combination the optimal treatment option
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