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Disclosure of interest: nothing to disclose Poster Session II - NOVEL TARGET/ EXPERIMENTAL FIDINGS TO CLINICAL TRANSLATION 06.00 - NOVEL TARGET/ EXPERIMENTAL FIDINGS TO CLINICAL TRANSLATION - 06.01 - PATHOPHYSIOLOGY OF STROKE / TRANSLATIONAL MEDICINE P1076 - ESOC25-2180 PROSPECTIVE OBSERVATIONAL EVALUATION OF PUPILLOMOTOR AUTONOMIC FUNCTION IN PATIENTS WITH ACUTE ISCHEMIC STROKE: RESULTS FROM THE APEX STUDY Daniela Schoene 1 , Lara Kretzschmar 1 , Daniel Kaiser 2 , Volker Puetz 1 , Kristian Barlinn 1 , Timo Siepmann 1 1 Department of Neurology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universitt Dresden, Dresden, Germany, 2 Institute of Neuroradiology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universitt Dresden, Dresden, Germany Background and Aims: Autonomic dysfunction is common after acute ischemic stroke (AIS), increasing mortality and worsening long-term outcome