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Clinical trial data shows eructation rates of approximately 4% for tirzepatide versus 7% for semaglutide at weight-loss doses

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[1] Notably, the FDA label advises that women using oral contraceptives should switch to a non-oral contraceptive method or add a barrier method for 4 weeks after initiation and for 4 weeks after each dose escalation of tirzepatide

The clinical evidence for cosmetic glutathione effects is mixed, and some medical bodies have cautioned against unsupervised high-dose use due to potential adverse effects over time