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Unfortunately, some alpha blockers cause ejaculatory problems, including retrograde ejaculation and even complete ejaculatory failure in some circumstances

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J Neuropathol Exp Neurol 66:1016 Deng H, Shi Y, Furukawa Y et al (2006) Conversion to the amyotrophic lateral sclerosis phenotype is associated with intermolecular linked insoluble aggregates of SOD1 in mitochondria