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When you should NOT take your GLP-1 early There are specific situations where early dosing is a bad idea, regardless of how convenient it might be

Across 2,783 participants, GLP-1RAs were associated with: - Higher rates of MASH resolution without worsening fibrosis - Reduced liver fat and improved ALT, AST, and GGT levels - Significant decreases in body weight, BMI, waist circumference, HbA1c, and triglycerides While gastrointestinal side effects (nausea, vomiting, diarrhea) were more common, the overall benefit profile was substantial

Efficacy and safety of once-weekly GLP-1 receptor agonist albiglutide (HARMONY 2): 52 week primary endpoint results from a randomised, placebo-controlled trial in patients with type 2 diabetes mellitus inadequately controlled with diet and exercise

10.1155/2019/7419249 [DOI] [PMC free article] [PubMed] [Google Scholar] Chen X., Zhang C., Wang H., Xu J., Duan Z