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Neuronally produced GLP1 is transported to the axon terminals of the producing cells and is there stored in synaptic vesicles until its eventual release into the synaptic cleft, or in case of extrasynaptic release, into the brain parenchyma (Zheng et al., 2014)
In rodent models, a number of studies have found that GLP-/GIP dual agonists group mice have reduced fat mass, decreased circulating cholesterol, and lost weight, which has excellent weight loss effect
The answer lies in the psychology of diabetes
I look into anything that may be hindering your bodys own production of GLP-1 and look into other factors that may be preventing you from losing weight and feeling your best