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doi: 10.1016/S0925-4773(02)00118-1 71 SegerstolpeAPalasantzaAEliassonPAnderssonEMAndreassonACSunXet al

CONSUMER RESULTS* Overall Skin Condition 93% noticed skin looked renewed 84% saw that skin looked more toned Advanced Claims 89% noticed an improvement in lines & texture 86% felt firmer, tighter skin 86% saw an improvement in expression lines 84% saw that wrinkles were smoothed 83% noticed creases appeared shallower & forehead lines appeared smoother 82% saw tighter-looking skin 80% saw lines smoothed around the mouth & lips 79% noticed engraved imperfections appeared shallower 77% noticed that skin looked lifted 74% felt that skin looked dramatically younger 73% saw that deep-set wrinkles, including marionette lines & nasolabial folds were smoothed *Based on a consumer perception study on 102 women over 28 days Acyl-Glutathione: The Master Antioxidant Comprised of three amino acids, Glutathione is the body's main antioxidant and helps to reduce the look of deep creases and improve fragile skin by protecting, repairing and detoxifying

Personal or family history of melanoma: PT-141 only

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Methods We systematically searched PubMed, Embase and Cochrane for randomized controlled trials (RCTs) comparing GLP-1 receptor agonists versus