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In planta mutations of the cherI gene resulted in clear phenotypes (e.g., reduced phospho- and choline levels in fully developed leaves and stunted growth), but supplying cherI mutant plants with exogenous choline did not rescue these strong phenotypes (28)

However, some people have experienced lethargy, low blood pressure, and disorientation after taking high doses

The changes resulted in a decrease in serum GLP-1 along with insulin resistance and metabolic dysfunction

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