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Description

Contribution statement XC, RW and TH conceived and designed the research

For technical reasons, this was done in mid-colonic sections rather than the distal colon, as used previously 15

It is a stimulant-free thermogenic, meaning it supports metabolic activity without caffeine or other central nervous system stimulants.

How We Got Here GLP-1 (glucagon-like peptide-1) receptor agonists are a class of medicines that mimic the natural GLP-1 hormone to suppress appetite and regulate blood sugar, originally developed for type 2 diabetes and now approved for obesity