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The superiority of HFR with respect to OL-HDF has also been proven in some studies, where a significant decrease in most of the inflammatory and oxidative stress parameters is objectified.45 In conclusion, in most of the published studies (Table 3) the switch from HD to HFR led to an improvement in inflammation with a significant decrease in serum levels of CRP, IL-6, IL-1 and TNF and a significant increase in albumin and prealbumin

It doesn't sting too but don't let it sit in your skin for more than 5 minutes

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Iron modulators degrade FPN (the sole iron export protein) on macrophage surfaces, increasing intracellular iron content

10.1038/s41591-019-0404-8 145 LiT.ZhangZ.KolwiczS