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[DOI] [PMC free article] [PubMed] [Google Scholar] 16.Nejati P, Ghahremaninia A, Naderi F, Gharibzadeh S, Mazaherinezhad A

Additionally, neuronal noradrenaline (NA) and angiotensin II act on 2-adrenergic receptors (2A) for NA and AT1 for angiotensin II on pericytes

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The overlapping mechanisms create risk of excessive sedation and respiratory depression

While the majority of published data originates from the Sikiric laboratory in Zagreb, independent groups have increasingly contributed to the literature, and the peptide remains a subject of active investigation across multiple areas of preclinical science.