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[54] Despite the renoprotective effects, less common side effects of SGLT2 inhibitors, in general, include acute renal failure (ARF), diabetic ketoacidosis (DKA), fractures, and amputations (Figure 3)
Among patients with UC, those treated with GLP1RA had lower rates of corticosteroid use (46.6% vs 85.1%), hospitalization (40.9% vs 65.9%), intestinal resection (6.52% vs 20.8%), and mortality (4.6% vs 22%) compared with controls
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Since myocardial remodelling plays a crucial role in the development of heart failure, and a critical feature of heart failure is impaired cardiac calcium metabolism, this effect of TZP may be crucial in the cardioprotective mechanism
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