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The FDA considers allulose generally recognized as safe (GRAS) with an intake below 0.5 to 0.6 grams per kilogram of body weight per day

Emerging evidence demonstrates that tumor cells possess the ability to sense and interpret these signals through mechanosensors and mechanotransducers, including mechanosensitive ion channels (e.g., ion channels that belong to the transient receptor potential (TRP) family), ion transporters, focal adhesions, cytoskeletal elements, nuclear proteins, and transcription factors

PMID 32334036

Additionally, GABAergic neurons carry IFN- receptor 1, linking IFN- to inhibitory signaling and cognitive behaviors [111, 117]

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