10.1016/j.jacc.2006.04.088 62 JalaliF.FakhariF.SepehrA.ZafariJ.SarajarB
The identification of exendin-4 from Gila monster (Heloderma suspectum) saliva as a stable GLP-1 mimetic enabled appetite suppression and glycemic control in metabolic disease, driving the development of long-acting GLP-1 analogues and unimolecular agents that co-activate GLP-1 and GIP receptors (Mller et al., 2025)
One of the most promising drug classes in recent years is GLP-1 receptor agonists, including semaglutide (Wegovy, Ozempic) and tirzepatide (Zepbound, Mounjaro).These medications have revolutionized weight loss and diabetes management, with additional potential benefits in reducing risks for conditions like sleep apnea, cardiovascular disease, and even alcohol dependence
PTEN induced putative kinase 1 (PINK1) alleviates angiotensin II-induced cardiac injury by ameliorating mitochondrial dysfunction
Air-popped popcorn without butter, oil, or excessive salt is easier to digest and less likely to cause bloating or nausea