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The "energy footprint" of urban areas has always extended over increasingly large basins, shaping distant and detached territories and creating "reciprocal landscapes." For example, for much of the 20th century, hydropower production has particularly impacted alpine territories near urban areas, marginal and fragile regions both in socio-economic terms and in terms of representation and self-determination

94 The six lysine residues increase the rigidity of the molecules structure, thus allowing its drug properties to be improved

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Barde S, et al