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Physiological effects Physiological effects GLP-1 receptor activation produces multiple physiological effects that contribute to its therapeutic benefits in the management of diabetes and obesity

The phase 1b, 16-week, multiple-dose ascending trial (NCT05613387) showed a mean body weight reduction of 4.8%, 8.6% and 8.3% at OW doses of up to 2.4 mg, 4.8 mg and 9.0 mg, respectively [116]

Animals were housed at 24 2 C, 55 15% humidity, under a 12 h light/dark cycle, with ad libitum access to water and standard chow

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Overall, our findings suggest vaping suppresses PN-specific immune responses by preventing the development of antigen-specific B cell responses