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In vitro and in vivo effects of IGF-1 delivery strategies on tendon healing: a review

And you can probably guess why the liver is constantly processing and removing toxins and needs glutathione to support these detoxification efforts

Rosenstock JU, et al

We found that therapeutic doses decrease liver GSH by only modest amounts (10%), but that overdoses of 10 grams or more severely deplete liver GSH (Figure6)