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Factors conferring relative protection to children from the toxic effect of paracetamol overdose include increases in paracetamol sulphation capacity [44,45,46,47,48], relative immaturity of the CYP450 oxidation system [15, 46, 49, 51] and the larger relative liver volume found in children [59] but these theoretical mechanisms have not been confirmed

Weiduschat N, Mao X, Hupf J, Armstrong N, Kang G, Lange DJ, et al

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Maintain Suitable pH Conditions Copper peptide formulations typically perform well within a mildly acidic to neutral pH environment

Danailova Y, Velikova T, Nikolaev G, Mitova Z, Shinkov A, Gagov H, Konakchieva R