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When to seek further advice Speak to your GP or prescribing clinician if you: Are pregnant, breastfeeding, or planning to conceive, as weight loss medication is generally not appropriate during pregnancy Are taking other prescription medications, particularly immunosuppressants such as ciclosporin, as Orlistat can interact with these Experience severe or persistent nausea, vomiting, or abdominal pain while taking either treatment Have not lost at least 5% of your starting body weight after 12 weeks on Orlistat, as continued use is unlikely to be beneficial Have questions about whether a weight loss treatment is appropriate given your personal medical history Frequently Asked Questions Can you take Wegovy semaglutide tablets and Orlistat at the same time

To minimize the side effects, healthcare providers typically adopt a gradual dosage increase over a few weeks

Discuss your long-term plan with a qualified healthcare provider who can monitor your response and adjust dosing over time

The poster also includes a summary of key changes to ISO10993 update, and a QR code for you to ask the questions for the workstream to review

Introduction The weight loss revolution has arrived, and HealthRX is leading the charge with unprecedented overnight access to the most effective GLP-1 medications available in 2025