[DOI] [PMC free article] [PubMed] [Google Scholar] 65.Ast J., Arvaniti A., Fine N.H.F., Nasteska D., Ashford F.B., Stamataki Z., Koszegi Z., Bacon A., Jones B.J., Lucey M.A., et al
Our nanoBRET findings demonstrate that DA activation of the 2A -adrenergic receptor primarily results in recruitment of G i1 to the receptor with negligible -arrestin2 recruitment while NE treatment causes robust recruitment of both the G protein and -arrestin2
This option offers convenience for those who prefer swallowing pills over taking injections
Moreover, obesity has been reported to be associated with a less favorable response to disease-modifying therapies
Masjedi F, Keshtgar S, Agah F, Karbalaei N