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481,482 These advanced models facilitate the study of CSCTME interactions and enable the testing of immunotherapy combinations targeting both CSCs and their supportive niches

A deficiency can also cause issues such as diarrhea, nausea, vomiting, lack of appetite, weight loss, pale skin, numbness and tingling in your hands and feet, confusion, irritability, depression, and behavior changes

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Persistently raised B12 requires repeat testing, medication review, full blood count, and liver and renal function assessment

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