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In an 88-week trial, participants experienced no new side effects beyond the digestive adjustments of the first few months

Its also probably a good idea to avoid foods and drinks that can irritate the stomach until symptoms improve

The highest doses that produced the most weight loss also produced the most nausea

Emerging evidence suggests that tirzepatide may offer benefits beyond weight loss and glycemic control, potentially playing a role in protecting cardiovascular health

The interplay between disruptions in central or peripheral dopaminergic signalling and possible feedback mechanisms remains poorly understood and might have a critical role in multiple systemic diseases, such as Parkinson disease, that are affected by these pathways