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The nonproductive methylation of glycine to sarcosine, which is physiologically inert, allows an alternative demethylation of SAM (Fig

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Furthermore, Figure 4D confirmed that H 2 O 2 increased the content of cellular ROS, while both targeting peptides obviously reduced the fluorescence intensity of the cellular ROS probe compared to that of GHK, especially RGD-GHK inhibited approximately 40% of ROS production