This work was supported by grants from the European Unions Horizon Europe Research and Innovation Program under grant agreement 101080465 to A.B., P.F., R.J., J.D
Following a thorough analysis of our previous Phase 2b data and trial design, we believe that with the preferred modified release formulation and future trial design optimization, we can advance a competitive oral GLP-1 molecule into registration enabling studies, with the goal of addressing the present and persistent medical needs of people living with obesity. Participants in the study so far have included healthy adults aged 18 years or older and the results thus far have shown a profile that supports once-daily dosing, which is consistent with previous danuglipron studies
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Error bars, P values and statistical tests are reported in the figure captions